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體內(nèi)純化等級抗體-上海倍篤生物

來源: 發(fā)布時間:2025-03-20

Purified in vivo Grade

Antibodies

Meeting your in vivo and

in vitro low endotoxin needs


In vivo GOLD? and ***TINUM?

functional-grade antibodies and isotype controls

In vivo grade antibodies have a variety

of uses in biological research, from discovery of cell signaling pathways to manipulation of biological systems

in animal models

for pre-clinical studies.

In vivo functional

grade antibodies from Leinco Technologies have the highest

purity standards in the industry,

with low endotoxin levels,

and screening to ensure low aggregates. These

antibodies are produced

in our cGMP and ISO 9001:2015 / ISO 13485:2016 certified facility and are available in custom concentrations and package sizes. In vivo ***TINUM antibodies are also suitable

for animal injection as they are pathogen

free as determined by the IDEXX Impact

I PCR mouse pathogen profile

(see table below).


Specificationsin vivo GOLDTM Mabsin vivo ***TINUMTM   MabsBinding validation determined by WB, FC or ELISAYesYesEndotoxin level determined by the LAL method≤ 1.0 EU/mg≤ 0.5 EU/mgAntibody aggregation screening by analytical SEC≥ 95% monomer≥ 98% monomerPurity by SDS Page≥ 95%≥ 98%Formulation for in vivo useNo preservatives

No stabilizers

No carrier proteins

Sterile PBS pH 7.2 - No K+ or CA2+

Concentration: > 5mg/mLNo preservatives No stabilizers

No carrier proteins

Sterile PBS pH 7.2 - No K+ or CA2+ Concentration: > 5mg/mLMurine pathogen screeningNot applicable, see ***TINUM functional grade antibodiesPathogen tested (IMPACT1)

(see table)ApplicationsIn vivo functional studies and may be used for studies, as well as WB, FC, IF or IHCProduct preparationFunctional grade preclinical antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregatesStorage and handlingUse a manual defrost freezer and avoid repeated freeze-thaw cycles.

?1 month, 2 to 8 ℃ under sterile conditions, as supplied.

?12 months, -70 C under sterile conditions.


Lot-to-lot reproducibility of in vivo antibodies: RMP1-14


Purified Bulk in vivo Grade Antibodies



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